Molecular Pathologist

Job Purpose

• The Molecular Pathologist will be responsible for leading and delivering advanced molecular diagnostic services at the African Medical Centre of Excellence AMCE.
• This role is critical for supporting precision medicine by performing and interpreting molecular tests for the diagnosis, prognosis, and treatment guidance of cancers, infectious diseases, genetic disorders, and other conditions.
• The role holder will oversee all aspects of the molecular pathology laboratory, including test development, quality assurance, and result reporting.
• He/ She will demonstrate expert knowledge of molecular biology techniques, strong analytical skills, and a deep commitment to patient-centered diagnostic excellence.

Key Accountabilities/Responsibilities

Molecular Diagnostic Testing & Interpretation

• Perform and supervise a wide range of molecular tests, including PCR, real-time PCR, next-generation sequencing NGS, Sanger sequencing, fluorescence in situ hybridization FISH, and fragment analysis.
• Interpret complex molecular test results, correlating them with clinical, histological, and immunohistochemical findings.
• Provide diagnostic, prognostic, and predictive reports to guide targeted therapy, immunotherapy, and personalized treatment plans.

Test Development & Validation

• Develop, optimize, and validate new molecular assays to meet emerging clinical and research needs.
• Establish and maintain laboratory protocols, standard operating procedures SOPs, and reference ranges for all molecular tests.
• Lead the implementation of new technologies and platforms, ensuring rigorous analytical and clinical validation.

Quality Assurance & Regulatory Compliance

• Ensure the molecular pathology laboratory operates in compliance with international standards e.g., ISO 15189, CAP, CLIA and local regulatory requirements.
• Implement and monitor quality control QC and quality assurance QA programs, including regular proficiency testing and inter-laboratory comparisons.
• Maintain meticulous documentation for all tests, validations, and quality activities. Participate in internal and external audits.

Leadership, Line Management & Training

• Lead and manage a team of molecular technologists, scientists, and trainees within the molecular pathology laboratory.
• Conduct performance evaluations, delegate responsibilities, and foster a culture of excellence and continuous learning.
• Provide training and mentorship to laboratory staff, pathology residents, and medical students in molecular techniques and result interpretation.

Research & Innovation

• Collaborate with clinicians, oncologists, infectious disease specialists, and researchers on translational and clinical research projects.
• Contribute to the development of novel biomarkers and molecular signatures for disease diagnosis and monitoring.
• Publish findings in peer-reviewed journals and present at scientific conferences.

Collaboration, Consultation & Communication

• Consult with referring physicians and clinical teams to select appropriate molecular tests and interpret results in the context of patient care.
• Participate in multidisciplinary tumor boards, infectious disease meetings, and genetic counseling sessions.
• Communicate complex molecular findings clearly to clinicians, patients, and families with empathy and cultural sensitivity.
• Maintain accurate and timely records in the laboratory information system LIS and hospital electronic medical record EMR.

Qualifications & Experience

• Medical Degree MBBS/MD or equivalent or PhD in Molecular Biology, Genetics, or a closely related field from a recognized institution.
• Board Certification or Fellowship in Molecular Pathology e.g., American Board of Pathology – Molecular Genetic Pathology, Fellow of the West African College of Physicians in Chemical Pathology, or equivalent international certification.
• Valid medical license to practice in Nigeria or eligibility to obtain one.
• Minimum of 5 years of hands-on experience in a molecular pathology or molecular diagnostics laboratory, with proven expertise in NGS, PCR, FISH, and Sanger sequencing.
• Demonstrated experience in assay development, validation, quality assurance ISO 15189/CAP/CLIA, and laboratory management.
• Strong publication record in peer-reviewed journals is highly desirable. Experience in training laboratory staff and presenting at scientific conferences is an added advantage.

Must have skills

• Demonstrated experience in assay development, validation, quality assurance ISO 15189/CAP/CLIA

Method of Application

Interested and qualified? Go to The African Medical Centre of Excellence (AMCE) on hris.peoplehum.com to apply